Trends Identified
Synthetic biology
Synthetic biology may be the least known and most “disruptive” of the technologies in this study. In essence, it is the application of engineering principles to biology. It draws on a number of existing technologies to design and construct new biological systems that produce useful products or serve useful purposes. Current so ware helps bio-engineers use a growing online library of “biobricks” to design new genetic functions. Biobricks can be assembled by robots, or digital DNA les can be sent to a DNA printer; in either case, the new DNA is inserted into a living cell. The technology is proving to be very efficient.
For example, when genetic engineering (which modifies only a few genes at a time) was used to develop
a yeast to produce precursors to the an malarial drug, artemisinin, it took 150 person-years of work and $25 million. Using biobricks, however, a lab of 12 people produced 12 biological systems of comparable complexity in 3 months. Working in this field is becoming easier for researchers at all levels.
2013
Metascan 3 emerging technologies
Canada, Policy Horizons Canada
Bioinformatics
Bioinformatics involves storing, analyzing, modeling and sharing large amounts of biological data. Current applications of bioinformatics include DNA barcoding, new bioproducts (such as Millennium Asparagus and biodiesel), modeling disease outbreaks and personal genomics. Our capacity to analyze large amounts of data and our ability to affect traits in plants, animals and humans will increase dramatically. Consider the potential of a widespread medical device costing under $1,000 that sequences your genome, connects to online databases, profiles your genetic history and future, highlights your risk profile, and identifies opportunities to mitigate risks. Bioinformatics holds the promise of tailoring medical and drug treatments to the individual through preventative medicine, using biomarkers to model adverse drug reactions, and helping to understand the complex interplay between genetics and environment. Bioinformatics will fundamentally change the way we think of health care systems.
2013
Metascan 3 emerging technologies
Canada, Policy Horizons Canada
Tissue engineering
Tissue engineering uses synthetic or naturally grown biomaterials to replace damaged or defective tissues, such as bone, skin and even entire organs. Today, organs that can be regrown include skin, windpipes and bladders; in a decade, this list may expand to kidneys, livers and hearts. Stem cells may also be used to repair damaged or failing organs in place. The most immediate application for tissue engineering is in the area of human health for purposes of healing, replacement and augmentation. This technology will reduce the need for organ donation and eliminate transplant rejection as body parts are regrown or printed using the patient’s own cells. In the longer term, advances in skin, bone and muscle synthesis may even allow individuals to change their appearance and augment physical abilities.
2013
Metascan 3 emerging technologies
Canada, Policy Horizons Canada
Nanomaterials
Nano-scale systems often exhibit properties that improve upon or are much different from their human-scale varieties; for example, silver exhibits anti-bacterial properties at the nano-scale that are absent at the macro-scale. As scientists work with materials close to the molecular level, they can produce new and useful materials, such as nanocellulose and nanocarbon. Both have impressive performance characteristics, being respectively 10 and 50 times stronger than steel for their weight. Nanocoatings provide new ways to make structures self-cleaning, more durable and perhaps even able to receive, store and respond to stimuli. Other nanomaterials are excellent catalysts for making chemistry greener and cheaper. Over the next 15 years, nanomaterials will change the types of things we build and how we build them.
2013
Metascan 3 emerging technologies
Canada, Policy Horizons Canada
Nanodevices
Nanodevices are machines made of a number of molecular parts that do useful work (such as moving
or changing electrically, chemically or optically) in response to specific inputs. Examples include nanoelectromechanical systems (NEMS), nanosensors, nanocomputers and nanorobots. They have surprising energy-efficiency, power density, sensitivity and optical efficiency. Their small size also reduces production costs and increases the number of devices running in parallel, increasing speed. They are likely to be of most use in medical devices, although their small size may lead them to be treated as “smart” drugs. They are also likely to be components of human-scale devices to increase the performance or provide new abilities.
2013
Metascan 3 emerging technologies
Canada, Policy Horizons Canada
Nanosensors
Nanosensors, in particular, are set to have a huge impact. They may open the door to the development
of inexpensive, portable devices that can rapidly detect, identify and quantify biological and chemical substances. These may take the form of specific sensing devices, or may simply be features integrated into the next few generations of mobile phones. As such, nanosensors are expected to lead to revolutionary applications, including early disease detection, real-time health monitoring, the early and accurate detection of environmental pollutants and contaminants, and even biological or chemical weapons.
2013
Metascan 3 emerging technologies
Canada, Policy Horizons Canada
Nanotechnology for solar
Solar cells, cheaper now than they have ever been, are poised for significant improvement due largely to nanotechnology. High-efficiency multi-junction solar cells, infrared energy capture and wavelength-splitting designs may increase high-efficiency solar cell performance by 200-300%. Roll-to-roll printing of solar cells on plastic using photosynthetic inks will allow solar panels to be manufactured at significantly lower costs than even today’s low prices.
2013
Metascan 3 emerging technologies
Canada, Policy Horizons Canada
Nanotechnology for batteries
Batteries will improve through the use of enhanced nanomaterials and economies of scale. We expect higher capacities, much faster recharging, and greater longevity and significantly lower prices. Better and cheaper batteries could be the cornerstone technology to displace the internal combustion engine for passenger vehicles and support the transition to renewables in homes and businesses by addressing the intermittency of renewable energy sources like wind and solar. Using these technologies, buildings may become energy independent and solar-powered fueling stations could support the growing electric vehicle market.
2013
Metascan 3 emerging technologies
Canada, Policy Horizons Canada
Neurostimulation
Neurostimulation covers those technologies that stimulate, or block, certain parts of the nervous system, particularly within the brain. The technology is used to treat various severe neurological disorders, such as Parkinson’s disease, depression and insomnia. Neurostimula on can also be used to augment human cognitive function. Neurostimulation has historically been performed through both invasive (surgery) and non-invasive means (taking pills, electrical stimulation). Wearable headsets are now being marketed that work by adding a slight voltage to neurons, letting them fire more easily. These devices use transcranial direct current stimula on (tDCS), which has the potential to enhance language, learning, attention, problem solving, coordination and memory functions; help combat insomnia, anxiety, and depression; and manage pain. The future use of both “smart drugs” and tDCS could allow some people to gain a competitive advantage over others.
2013
Metascan 3 emerging technologies
Canada, Policy Horizons Canada
Brain-computer interface
A brain-computer interface (BCI) is a direct communication pathway that connects nerve signals in the brain to an external computer. BCIs can be invasive (implanted within or just above the brain), or non-invasive (on the scalp surface). BCIs are used therapeutically to assist, augment or repair human cognitive, sensory or motor functions. Today, it requires training and practice to make BCIs useful and reliable. Research, artificial intelligence and more data, however, will improve this significantly. Potential near-term applications include the use of BCIs to detect lapses in attention among occupations requiring vigilance, and as a communication tool for those who have lost motor skills but retained cognition. In the future, this technology could be used to improve cognitive functions, to better understand human preferences, and to augment human capabilites such as coordination and response times. It may even be used to develop senses new to humans, such as the ability to sense magnetic fields, infrared light or radio waves.
2013
Metascan 3 emerging technologies
Canada, Policy Horizons Canada